반응 #1269835

반응 방정식

water

1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene

1,1-dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene

hydrazine hydrate

→

3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole

용매

Ethanol

ethanol

반응 조건

후처리

1. 1
   온도heated on the steambath for 1 hour
2. 2
   기타The precipitated solid is collected
3. 3
   세척washed with ethanol:water (4:1)
4. 4
   기타dried in air

실험 절차

1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene (22.5 g) and 1,1-dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene oil (15 g) are treated with a solution of hydrazine hydrate (18 mL) in ethanol (25 mL) and heated on the steambath for 1 hour. Ethanol (15 mL) is added followed by water (10 mL). The precipitated solid is collected and washed with ethanol:water (4:1) and then dried in air to give 3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole as a pale orange solid.

출처