반응 #1263660

반응 방정식

tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate

1-(3-bromopropoxy)-4-fluorobenzene

→

title compound

tert-Butyl 4-{4-[3-(4-fluorophenoxy)propoxy]phenyl}-3-hydroxypiperidine-1-carboxylate

반응 조건

실험 절차

Analogously to Method I, 0.750 g of tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate and 0.758 g of 1-(3-bromopropoxy)-4-fluorobenzene are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.13 (1:2 EtOAc-heptane); Rt=5.12.

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