반응 #1253203

반응 방정식

chlorine

3,4-dimethyl-2-pyrazolin-5-one

→

3,4-dimethyl-4-chloro-2-pyrazolin-5-one

용매

1,2-dichloroethane

반응 조건

후처리

1. 1
   기타After the reaction
2. 2
   온도the reaction mixture was cooled
3. 3
   여과filtered
4. 4
   workup.DISTILLATIONThe solvent was then distilled off
5. 5
   기타The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether

실험 절차

A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.

출처