반응 #1246015

반응 방정식

[3-(2-cyano-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indol-6-yl]-methyl-carbamic acid tert-butyl ester

→

2-(6-Methylamino-1-pyridin-2-ylmethyl-1H-indol-3-ylsulfanyl)-benzonitrile

용매

toluene acetone

반응 조건

후처리

1. 1
   기타the product obtained in the previous step (0.150 g, 0.33 mmol)
2. 2
   기타to give

실험 절차

v)—Following a procedure analogous to that described under step i of Example 2, the product obtained in the previous step (0.150 g, 0.33 mmol) was methylated to give, after column chromatography (toluene/acetone 8:2), [3-(2-cyano-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indol-6-yl]-methyl-carbamic acid tert-butyl ester (0.044 g).

출처