반응 #1214

반응 방정식

N-methylethanolamine

glycidyl tetradecanate

→

title compound

수율 60.8%

3-[N-(2-hydroxyethyl)-N-methylamino]-2-hydroxy-1-propyl tetradecanate

수율 60.8%

용매

ethanol

반응 조건

후처리

1. 1
   기타A 100-ml flask equipped with a stirrer
2. 2
   기타The resultant reaction mixture
3. 3
   농축was concentrated under reduced pressure
4. 4
   기타the residue was purified by chromatography on silica gel

실험 절차

A 100-ml flask equipped with a stirrer and dropping funnel was charged with 6.01 g (80 mmol) of N-methylethanolamine, 50 ml of ethanol and 22.8 g (80 mmol) of glycidyl tetradecanate, and the contents were stirred at 80° C. for 2 hours. The resultant reaction mixture was concentrated under reduced pressure, and the residue was purified by chromatography on silica gel, thereby obtaining 17.5 g (yield: 60.8%) of the title compound (IIe-2).

출처