반응 #12070

반응 방정식

triethylamine

4-vinylbenzyl chloride

monomethyl malonitrile

DMSO

→

pinkish crystals

수율 64.0%

4-(2,2′-dicyanopropyl) styrene

수율 64.0%

용매

water

반응 조건

후처리

1. 1
   기타A pink solid precipitated
2. 2
   여과was filtered
3. 3
   기타The solid was recrystallized from a mixture of methanol and water

실험 절차

A sample (2.53 g) of triethylamine (25 mmol) was added dropwise to a mixture of 4.01 g 4-vinylbenzyl chloride (25 mmol), 2.00 g monomethyl malonitrile (25 mmol), and 15 mL DMSO at room temperature. The mixture was stirred at room temperature for 17 hours then poured into 100 mL water. A pink solid precipitated and was filtered. The solid was recrystallized from a mixture of methanol and water to give 3.141 g (64%) of pinkish crystals.

출처