반응 #11965

반응 방정식

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

수율 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

수율 189.4%

용매

methanol

반응 조건

후처리

1. 1
   기타After the reaction
2. 2
   기타the solvent was removed by distillation
3. 3
   기타the residue was dried

실험 절차

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

출처