반응 #1195685

ord-5321f1854cab439f871ea06170045f9c

반응 방정식

O=C(O)/C=C/c1cnc[nH]1
urocanic acid
CO
methanol
COC(=O)C=Cc1c[nH]cn1
crude product 2
COC(=O)C=Cc1c[nH]cn1
methyl 3-(4-imidazolyl)-2-propenoate

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타was bubbled HCl gas until the solution
  2. 2
    농축concentrated in vacuo to dryness

실험 절차

Through a suspension of urocanic acid (5.0 g) in methanol at 0° C. was bubbled HCl gas until the solution was saturated. The reaction was stirred for one hour, then concentrated in vacuo to dryness to provide the crude product 2 which was used in the next step without further purification.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06066738uspto-grants-2000_05