반응 #1194

반응 방정식

ethanolamine

10-(2-ethylhexyloxy)decyl glycidyl ether

→

title compound

수율 68.4%

1-(2-hydroxyethylamino)-3-[10-(2-ethylhexyloxy)decyloxy]-2-propanol

수율 68.4%

용매

ethanol

반응 조건

후처리

1. 1
   기타A 200-ml two-necked flask equipped with a stirrer
2. 2
   온도reflux tube
3. 3
   온도While heating
4. 4
   workup.STIRRINGstirred further for 18 hours
5. 5
   농축it was concentrated under reduced pressure
6. 6
   기타the resultant residue was purified by column chromatography on silica gel

실험 절차

A 200-ml two-necked flask equipped with a stirrer, reflux tube and dropping funnel was charged with 32.7 g (0.54 mol) of ethanolamine and 10.1 g of ethanol. While heating and stirring the mixture at 80° C., 1.76 g (5.14 mmol) of 10-(2-ethylhexyloxy)decyl glycidyl ether were added dropwise over 2 hours. After the resultant mixture was heated and stirred further for 18 hours, it was concentrated under reduced pressure, and the resultant residue was purified by column chromatography on silica gel, thereby obtaining 1.42 g (yield: 68%) of the title compound (Ia-14).

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