반응 #1192

반응 방정식

2-ethylhexyl bromide

1,10-decanediol

KOH

→

10-(2-ethylhexyloxy)decanol

수율 72.1%

용매

xylene

반응 조건

후처리

1. 1
   기타A 1-liter flask equipped with a stirrer
2. 2
   workup.DISTILLATIONdistilling off water
3. 3
   기타formed
4. 4
   온도the resulting mixture was heated
5. 5
   기타After completion of the reaction
6. 6
   세척washed with water
7. 7
   workup.DISTILLATIONAfter the solvent was distilled off under reduced pressure
8. 8
   기타the resulting residue was purified by column chromatography on silica gel

실험 절차

A 1-liter flask equipped with a stirrer and distiller was charged with 25 g (0.14 mol) of 1,10-decanediol, 8.09 g (0.14 mol) of KOH and 300 ml of xylene, and the resultant mixture was heated at 120° C. for 1 hour, thereby distilling off water formed. To this reaction mixture, were added 23.1 g (0.12 mol) of 2-ethylhexyl bromide, and the resulting mixture was heated and stirred for 15 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and washed with water. After the solvent was distilled off under reduced pressure, the resulting residue was purified by column chromatography on silica gel, thereby obtaining 24.8 g (yield: 72%) of 10-(2-ethylhexyloxy)decanol.

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