반응 #11852

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4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidine-2-amine

benzyl isocyanate

→

title compound

수율 19.1%

N-benzyl-N′-(4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidin-2-yl)urea

수율 19.1%

용매

THF

반응 조건

후처리

1. 1
   여과the resulting solid filtered
2. 2
   세척washed with EtOAc

실험 절차

A solution of 4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidine-2-amine (192 mg, 0.96 mmol) in THF (3 mL) was treated with benzyl isocyanate (118 μL, 0.96 mmol), stirred at room temperature for 16 h and the resulting solid filtered and washed with EtOAc to give the title compound (61 mg, 19%) as a yellow solid.

출처