반응 #1182393

ord-04e62ed7d1534d5da5af119163eb80c6

반응 방정식

O=C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O
galacturonic acid
O=C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO
galactose
C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)C=O
rhamnose
O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
glucose
O=C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO
galactose
O=C[C@@H](O)[C@H](O)[C@H](O)CO
arabinose

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The high yield
  2. 2
    추출an extract of the Astragalus membranaceus
  3. 3
    기타produced
  4. 4
    추출extract at a temperature and time

실험 절차

The teachings also provide a method of preparing the extracts. The methods comprise isolating a crude extract from Astragalus membranaceus and mildly treating the crude extract with an acid. The mildly treating includes applying the acid to the crude extract at a concentration ranging from about 0.05M to about 0.5M, at a temperature ranging from about 15° C. to 25° C., and for a time ranging from about 1 hour to about 24 hours. The temperature and time for applying the acid are selected to obtain an arabinose:galactose ratio greater than about 3.5:1; from about 5% to about 10% rhamnose; from about 15% to about 20% galactose; from about 10% to about 20% galacturonic acid; from about 10% to about 15% glucose; and a high yield. The high yield is substantially higher than a yield of an extract of the Astragalus membranaceus produced using a second process that includes applying the acid to the crude extract at a temperature and time selected to obtain an arabinose:galactose ratio of less than 3.5:1, 20%-35% galactose, and less than about 10% glucose. In some embodiments, the arabinose:galactose ratio can reduced to within a range of about 4.0:1 to about 4.5:1, about 3.75:1 to about 4.5:1, about 3.8:1 to about 4.25:1, or any range therein.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08137710B2uspto-grants-2012_03