반응 #1176799

반응 방정식

allyl ether

→

2,3-dihydro-4-methyl-6-(propen-3-yl) 5-benzofuranol

용매

1,2-dichlorobenzene

반응 조건

후처리

1. 1
   기타to afford
2. 2
   기타after chromatographic purification, compound 37
3. 3
   기타Recrystallization from hexane
4. 4
   기타gave an analytical sample

실험 절차

In a manner analogous to that described above for 2a, 36 (1.00 g, 6.66 mmol) was alkylated with allyl bromide (1.76 g, 14.6 mmol) to give the allyl ether. The allyl ether (1.23 g) was thermally rearranged in 1,2-dichlorobenzene (8 mL) at 190° C. for 3.5 hours to afford, after chromatographic purification, compound 37. Recrystallization from hexane gave an analytical sample. 37: mp 60°-61° C.

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