반응 #1166468

반응 방정식

2-(aminoethoxy)ethanol

hexahydrophthalic anhydride

→

N-(2-hydroxyethoxyethyl)hexahydrophthalimide

수율 96.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타A 500-ml, two necked flask was equipped with a magnetic stirring bar
2. 2
   온도heating mantle and condenser
3. 3
   workup.ADDITIONAfter the addition
4. 4
   온도was refluxed for 12 hours
5. 5
   기타The ethanol was removed with a rotoevaporator

실험 절차

A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy)ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.

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