반응 #11637

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4-(2-pyrrolidin-1-yl-ethoxy)-phenylamine

4-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

수율 77.1%

4-Fluoro-3-{[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-methylene}-1,3-dihydro-indol-2-one

수율 77.1%

반응 조건

실험 절차

In a manner similar to that described in Example 231, 4-(2-pyrrolidin-1-yl-ethoxy)-phenylamine (690 mg, 1.2 equiv.) and 4-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 2.79 mmol, 1 equiv.) to give the named compound as a yellow solid (790 mg, 77.0%).

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