반응 #11617

반응 방정식

4-(3-diethylamino-propoxy)-3-fluoro-phenylamine

6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

수율 32.4%

3-{[4-(3-Diethylamino-propoxy)-3-fluoro-phenylamino]-methylene}-6-fluoro-1,3-dihydro-indol-2-one

수율 32.4%

반응 조건

후처리

1. 1
   기타are reacted

실험 절차

In a manner similar to that described in Example 231, 4-(3-diethylamino-propoxy)-3-fluoro-phenylamine (400 mg, 1.1 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (269 mg, 1.5 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (195 mg, 32%).

출처