반응 #11613

반응 방정식

4-(4-piperidin-1-yl-butoxy)-phenylamine

6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

수율 73.0%

6-Fluoro-3-{[4-(4-piperidin-1-yl-butoxy)-phenylamino]-methylene}-1,3-dihydro-indol-2-one

수율 73.0%

반응 조건

후처리

1. 1
   기타are reacted

실험 절차

In a manner similar to that described in Example 231, 4-(4-piperidin-1-yl-butoxy)-phenylamine (400 mg, 1.1 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (263 mg, 1.47 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (435 mg, 73%).

출처