반응 #1146874

반응 방정식

2-(4-trifluoromethoxyphenyl)ethylamine

triethylamine

4-chloro-6-(1-chloroethyl)-5-iodopyrimidine

→

6-(1-chloroethyl)-5-iodo-4-[2-(4-trifluoromethoxyphenyl)ethylamino]pyrimidine

용매

toluene

반응 조건

실험 절차

In toluene (50 ml) were dissolved 2-(4-trifluoromethoxyphenyl)ethylamine (1.0 g) and triethylamine (1.0 g), then, 4-chloro-6-(1-chloroethyl)-5-iodopyrimidine (1.5 g) was added to the solution, and the mixture was heated at about 60° C. for 3 hours while stirring.

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