반응 #1144428

반응 방정식

1-(methoxymethyl)-6-phenylthiothymine

→

target compound

수율 28.1%

6-phenylthiothymine

수율 28.1%

용매

hydrochloric acid

반응 조건

후처리

1. 1
   기타to react for 2 hours at 80° C
2. 2
   농축The reaction mixture was concentrated under reduced pressure
3. 3
   기타crystallized from ethanol

실험 절차

To 100 ml of concentrated hydrochloric acid, 17.2 g (62 mmole) of 1-(methoxymethyl)-6-phenylthiothymine was added and allowed to react for 2 hours at 80° C. The reaction mixture was concentrated under reduced pressure and crystallized from ethanol to obtain 3.8 g of the target compound (Yield: 26%).

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