반응 #11397

반응 방정식

1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid

4-amino-3-ethylpiperidine

→

titled product

수율 71.0%

1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(4′-amino-3′-ethylpiperidin-1-yl)-4-oxo-naphthyridine-3-carboxylic acid

수율 71.0%

용매

acetonitrile

반응 조건

실험 절차

The condensation of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid with 4-amino-3-ethylpiperidine was carried out in acetonitrile in a similar manner as described in example 1, gave the titled product. Yield 71%, m.p 218–20° C., C19H23FN4O3, m/z 375 (M+1).

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