반응 #1135838

반응 방정식

1-fluoro-2-nitrobenzene

cyclopropyl amine

→

N-cyclopropyl-2-nitroaniline

수율 96.2%

용매

ethanol

반응 조건

후처리

1. 1
   농축concentrated
2. 2
   기타The residue was purified by biotage column chromatography

실험 절차

To a solution of 1-fluoro-2-nitrobenzene (0.50 g, 3.5 mmol) in ethanol was added cyclopropyl amine (0.60 g, 10.5 mmol). The solution was heated to 80° C. overnight and concentrated. The residue was purified by biotage column chromatography to give N-cyclopropyl-2-nitroaniline (0.60 g)

출처