반응 #11358

반응 방정식

5-benzyloxy-2-ethoxybenizonitrile

5-Benzyloxy-2-ethoxybenzonitrile

→

Ethoxy-5-hydroxybenzonitrile

용매

methanol

반응 조건

후처리

1. 1
   여과The mixture is filtered through kieselguhr
2. 2
   기타evaporated
3. 3
   기타the crystalline residue is dried under reduced pressure

실험 절차

40.02 g of 5-benzyloxy-2-ethoxybenizonitrile (158 mmol) (example 32A) and 5% Pd/C (4.0 g) are initially charged in 1 l of methanol. The mixture is then hydrogenated under an atmosphere of hydrogen (1 atm) for about 4 h. The mixture is filtered through kieselguhr and evaporated and the crystalline residue is dried under reduced pressure.

출처