반응 #11356

반응 방정식

2-hydroxybenzonitrile

potassium carbonate

ethyl bromide

→

2-Ethoxybenzonitrile

용매

acetone

반응 조건

후처리

1. 1
   여과The solid is filtered off
2. 2
   기타the solvent is removed under reduced pressure
3. 3
   workup.DISTILLATIONthe residue is distilled under reduced pressure

실험 절차

25 g (210 mmol) of 2-hydroxybenzonitrile, 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide are refluxed in 500 ml of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure. This gives 30.0 g (97%) of a colorless liquid.

출처