반응 #1128908

반응 방정식

6,7-dichloro-1H-indole-2,3-dione

acetic anhydride

→

7,8-dichloro-1H-benzo[d][1,3]oxazine-2,4-dione

용매

반응 조건

후처리

1. 1
   workup.ADDITIONAfter addition
2. 2
   온도cooled down to room temperature
3. 3
   여과Filtration

실험 절차

To a mixture of 6,7-dichloro-1H-indole-2,3-dione (4.95 g) in 25 mL glacial acid and 25 mL acetic anhydride was added chromium (VI) oxide (3.9 g, 39 mmol) portionwise at 85° C. After addition, the mixture was stirred at 90° C. for 30 min. and cooled down to room temperature. Filtration provided a small amount of 7,8-dichloro-1H-benzo[d][1,3]oxazine-2,4-dione. Evaporation of the filtrate gave the majority of the product as a green solid containing chromium (III) oxide.

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