반응 #1126303

반응 방정식

methyl hydrazinecarbothioate

piperidin-4-ol

ethyl acetate

→

crude desired product

1-hydrazinothiocarbonylpiperidin-4-ol

용매

ethanol

반응 조건

후처리

1. 1
   세척the reaction solution was washed with saturated aqueous sodium chloride
2. 2
   건조dried over anhydrous magnesium sulfate
3. 3
   농축concentrated

실험 절차

A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.

출처