반응 #1114287

반응 방정식

3-ethoxycarbonyl-7-(4-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid

3-Ethoxycarbonyl-7-(4-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid

6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride

→

title compound

수율 89.1%

3-Ethoxycarbonyl-6-(6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]-1′-ylcarbonyl)-7-(4-methylphenylamino)pyrazolo[1,5-a]pyrimidine

수율 89.1%

반응 조건

실험 절차

In the same manner as in Example 21, step 5 and using 3-ethoxycarbonyl-7-(4-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.060 g, 0.176 mmol) obtained in step 2 and 6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride (0.040 mg, 0.194 mmol), the title compound (0.083 g, 89%) was obtained.

출처