반응 #1114273

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3-ethoxycarbonyl-7-(3-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid

3-Ethoxycarbonyl-7-(3-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid

6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride

→

title compound

수율 64.3%

3-Ethoxycarbonyl-6-(6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]-1′-ylcarbonyl)-7-(3-methylphenylamino)pyrazolo[1,5-a]pyrimidine

수율 64.3%

반응 조건

실험 절차

In the same manner as in Example 21, step 5 and using 3-ethoxycarbonyl-7-(3-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.130 g, 0.382 mmol) obtained in step 2 and 6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride (0.087 g, 0.420 mmol), the title compound (0.130 g, 64%) was obtained.

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