반응 #1114270

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7-benzylamino-3-bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid

7-Benzylamino-3-bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid

6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride

→

title compound

수율 77.8%

7-Benzylamino-3-bromo-6-(6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]-1′-ylcarbonyl)pyrazolo[1,5-a]pyrimidine

수율 77.8%

반응 조건

후처리

1. 1
   기타obtained in Reference Example 4

실험 절차

In the same manner as in Example 21, step 5 and using 7-benzylamino-3-bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (0.193 g, 0.556 mmol) obtained in Example 22, step 3 and 6-fluoro-2H-spiro[benzofuran-3,4′-piperidine]hydrochloride (0.150 g, 0.616 mmol) obtained in Reference Example 4, the title compound (0.232 g, 77%) was obtained.

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