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7-chloro-3-ethoxycarbonyl-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine

7-Chloro-3-ethoxycarbonyl-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine

2,5-dimethylaniline

→

title compound

수율 103.1%

7-(2,5-Dimethylphenylamino)-3-ethoxycarbonyl-6-(4- phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine

수율 103.1%

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실험 절차

In the same manner as in Example 19, step 5 and using 7-chloro-3-ethoxycarbonyl-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine (0.10 g, 0.23 mmol) obtained in Example 81, step 2 and 2,5-dimethylaniline (0.042 g, 0.35 mmol), the title compound (0.118 g, 99%) was obtained.

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