반응 #1106682

반응 방정식

C-Benzo[1,3]dioxol-2-yl-methylamine

sulfamide

→

title compound

(Benzo[1,3]dioxol-2-ylmethyl)sulfamide

용매

dioxane

반응 조건

후처리

1. 1
   온도the solution was heated
2. 2
   온도to reflux overnight
3. 3
   농축The reaction was concentrated
4. 4
   기타the residue was chromatographed (2% to 10% acetone in dichloromethane)

실험 절차

C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.

출처