반응 #11040

반응 방정식

2,7-dichloromethyl-3,6-di-t-butylfluorene

LiAlH4

→

2,7-di-methyl-3,6-di-tert-butyl-fluorene

수율 85.0%

용매

THF

반응 조건

후처리

1. 1
   온도the mixture was refluxed for 4 hours
2. 2
   기타The reaction was quenched with water and NaOH
3. 3
   추출extracted with ether
4. 4
   기타The ether solution was evaporated under vacuum

실험 절차

To a solution of 2,7-dichloromethyl-3,6-di-t-butylfluorene (0.75 g, 2.0 mmol) in THF (15 ml) was added a small portion of LiAlH4 (220 mg, 5.8 mmol) under stirring and the mixture was refluxed for 4 hours. The reaction was quenched with water and NaOH and extracted with ether. The ether solution was evaporated under vacuum to give a white solid of 2,7-di-methyl-3,6-di-tert-butyl-fluorene with a yield of 85%.

출처