반응 #1102
ord-7b74a27dcc2940b5b3a704ddbd2de98d
반응 방정식
water
4-(4-oxocyclohexylamino)-3-methoxy-2-methylpyridine
O-benzylhydroxylamine
ethyl acetate methanol
water
→
4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine
반응물
시약
없음
용매
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
2 g of 4-(4-oxocyclohexylamino)-3-methoxy-2-methylpyridine and 1.2 g O-benzylhydroxylamine are boiled in toluene in a water separator until liberation of water has ended. The product is isolated by column chromatography (ethyl acetate/methanol 9:1; silica gel). 1.8 g=53%