반응 #1099220

반응 방정식

2-[(4-chloro-2-{(E)-[4-(diethylamino)phenyl]diazenyl}-1,3-thiazol-5-yl)methylene]-1H-indene-1,3(2H)-dione

1-methylpiperazine

→

2-{[2-{(E)-[4-(diethylamino)phenyl]diazenyl}-4-(4-methyl-1-piperazinyl)-1,3-thiazol-5-yl]methylene}-1H-indene-1,3(2H)-dione

용매

tetrahydrofurane

반응 조건

후처리

1. 1
   온도heated
2. 2
   기타consumption of the starting material
3. 3
   여과was filtered off
4. 4
   세척washed with THF
5. 5
   기타dried in vacuum at 40° C.
6. 6
   기타to obtain a dark green powder

실험 절차

1.00 g (2.20 mmol) 2-[(4-chloro-2-{(E)-[4-(diethylamino)phenyl]diazenyl}-1,3-thiazol-5-yl)methylene]-1H-indene-1,3(2H)-dione and 0.30 g (2.70 mmol) 1-methylpiperazine were dissolved in 40 ml tetrahydrofurane (THF) and heated under stirring for 5 hours when thin layer chromatography (TLC) analysis indicated complete consumption of the starting material. After cooling to room temperature the formed precipitate was filtered off, washed with THF and dried in vacuum at 40° C. to obtain a dark green powder.

출처