반응 #1092140

반응 방정식

5-methyl-benzo[b]furan

N-bromosuccinimide

5-bromomethyl-benzo[b]thiophene

5-methyl-benzo[b]thiophene

→

5-bromomethyl-benzo[b]furan

용매

carbon tetrachloride

반응 조건

실험 절차

By brominating 5-methyl-benzo[b]furan[Synth. Commun. 19, 257(1989)] with N-bromosuccinimide in carbon tetrachloride in an analogous manner to the procedure for the preparation of 5-bromomethyl-benzo[b]thiophene [J. Med. Chem. 34(1), 65(1991)] from 5-methyl-benzo[b]thiophene there was obtained 5-bromomethyl-benzo[b]furan as a light yellow solid; MS: 210, 212 (M)+.

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