반응 #10910

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cyanamide

1-(4-isothiocyanatophenyl)-4-isopropypiperazine

1-(4-isothiocyanatophenyl)-4-(1-methylethyl)piperazine

3-cyanophenacyl bromide

→

3-{4-Amino-2-[4-(4-isopropyl-piperazin-1-yl)-phenylamino]-thiazole-5-carbonyl}-benzonitrile

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실험 절차

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-isopropypiperazine (of Example 3) and 3-cyanophenacyl bromide (Maybridge Chemical Co. Ltd.) following the procedure used in Example 24. Mass spectrum (ES) MH+=447.

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