반응 #1080232

반응 방정식

3-(4-Methoxyphenyl)propionic acid

thionyl chloride

→

product

3-(4-Methoxyphenyl)propionyl Chloride

용매

toluene

반응 조건

후처리

1. 1
   기타The solvent is evaporated off under reduced pressure
2. 2
   workup.DISSOLUTIONthe residue is redissolved in toluene
3. 3
   농축concentrated to dryness

실험 절차

To a suspension of 3-(4-Methoxyphenyl)propionic acid (10 g) in 150 ml of toluene are added 8 ml of thionyl chloride and the mixture is heated to 65° C. for 4 hours. The solvent is evaporated off under reduced pressure and the residue is redissolved in toluene and concentrated to dryness. Such steo is repeated twice. 11 g of the product are obtained as a yellow oil.

출처