반응 #10747

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2,4-dimethoxy-6-thiophen-2-yl-benzaldehyde

4-acetylbenzoic acid

→

title compound

수율 61.0%

4-[3E-(2,4-Dimethoxy-6-thiophen-2-yl-phenyl)-acryloyl]-benzoic acid

수율 61.0%

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실험 절차

The title compound was prepared by condensing 2,4-dimethoxy-6-thiophen-2-yl-benzaldehyde (Ex-39A) and 4-acetylbenzoic acid in a similar manner as described in Ex-3. Yellow solid, 61% yield, mp 231° C. (dec.). 1H-NMR (DMSO-d6) δ 8.02 (d, 2H), 7.93 (d, 2H), 7.73 (m, 3H), 7.15 (t, 1H), 7.07 (d, 1H), 6.72 (d, 1H), 6.62 (d, 1H). MS m/z=394 ([M]+, 6%), 245 (100%). HRMS m/z: calc. 395.0953, found 395.0949.

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