반응 #10700

반응 방정식

maleimide

HCOH

NaOH

→

hydroxymethylmaleimide

반응 조건

후처리

1. 1
   기타reacted at 40° C. for 2 hours
2. 2
   기타As a result, a white crystal of hydroxymethylmaleimide precipitates
3. 3
   여과This white crystal is filtered under reduced pressure
4. 4
   기타dried at normal temperature under vacuum

실험 절차

24 Parts of maleimide (manufactured by Aldrich Corporation), 21 parts of 35% HCOH (manufactured by Wako Pure Chemical Industries, Ltd.) and 0.7 parts of a 5% aqueous NaOH solution are placed in a reactor and reacted at 40° C. for 2 hours. As a result, a white crystal of hydroxymethylmaleimide precipitates. This white crystal is filtered under reduced pressure and then dried at normal temperature under vacuum. The crude crystal of hydroxymethylmaleimide obtained in this manner is recrystallized from ethyl acetate to obtain 22 parts of hydroxymethylmaleimide.

출처