반응 #1062083

반응 방정식

5-benzyl-4,6-dioxo-octahydropyrrolo[3,4-b]pyrrole

lithium aluminum hydride

→

5-Benzyl-octahydropyrrolo[3,4-b]pyrrole

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   workup.DISTILLATIONWorking up by distillation
2. 2
   기타gives 21.0 g (41.1% of theory) of an oil of boiling point 95° C./0.1 mbar

실험 절차

57.7 g (0.25 mol) of crude 5-benzyl-4,6-dioxo-octahydropyrrolo[3,4-b]pyrrole are reduced with 21.4 g (0.56 mol) of lithium aluminum hydride by boiling in 700 ml of absolute tetrahydrofuran for 10 hours in accordance with the working instructions of Example Ic. Working up by distillation gives 21.0 g (41.1% of theory) of an oil of boiling point 95° C./0.1 mbar.

출처