반응 #1052049

반응 방정식

Tetrafluorophthalic anhydride

N,N-dimethylformamide

pyridine

hydrazine

→

Compound 43

수율 87.0%

tetrafluorophthalhydrazide

수율 87.0%

반응 조건

후처리

1. 1
   농축The reaction mixture is concentrated in vacuo
2. 2
   workup.ADDITIONthe residue is poured into water (200 mL)
3. 3
   기타The precipitate formed
4. 4
   여과is collected by filtration
5. 5
   세척washed with water
6. 6
   기타air-dried

실험 절차

Tetrafluorophthalic anhydride (400 mg, 1.8 mmol) is dissolved in 10 mL of anhydrous N,N-dimethylformamide (DMF) that contains anhydrous pyridine (0.47 mL, 5.8 mmol). To the solution is slowly added hydrazine (64 mg, 2.0 mmol). The resulting mixture is stirred overnight. The reaction mixture is concentrated in vacuo, and the residue is poured into water (200 mL). The precipitate formed is collected by filtration, washed with water and air-dried to give Compound 43 (369 mg, yield: 87%).

출처