반응 #1033
ord-3730779ac7234e61924027d44b783970
반응 방정식
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) with ethyl vinyl ether in the presence of sodium hydrosulfite/sodium bicarbonate followed by oxidation of the intermediate, 4-bromo-3-chloro-3,4,4-trifluorobutanal (VII), without isolaton, with sodium chlorite/hydrogen peroxide to give 4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid (VIII) in overall unexpected yields;