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6-(isobutylsulfonyl)picolinic acid

(S)-5-methyl-α-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine hydrochloride

(2S)-2-[(tert-butoxycarbonyl)amino]-4-methylpentanoic acid

→

title compound

6-(2-Methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid [(S)-3-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-butyl]-amide

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실험 절차

The title compound was synthesized in analogy to Example 1, using 6-(isobutylsulfonyl)picolinic acid (Example 330 b) and (S)-5-methyl-α-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine hydrochloride (which was prepared from (2S)-2-[(tert-butoxycarbonyl)amino]-4-methylpentanoic acid (CAN 13139-15-6) in analogy to the procedures described in Example 38 a to e) as starting materials. MS (EI): m/e=395.2 [M+H]+.

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