반응 #10139

반응 방정식

3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid dimethyl ester

3-(2-methoxy-ethylamino)-phthalic acid

HCl

→

3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid

반응 조건

후처리

1. 1
   기타reaction mixture
2. 2
   기타The solvent was then evaporated in vacuo
3. 3
   기타leaving a dry salt mixture that
4. 4
   기타was used without further purification

실험 절차

3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid dimethyl ester (0.91 g, 3.03 mmol) was treated in the same manner as described above for the synthesis of 3-(2-methoxy-ethylamino)-phthalic acid except the pH of crude reaction mixture was adjusted to 2–3 by dropwise addition of concentrated HCl. The solvent was then evaporated in vacuo leaving a dry salt mixture that was used without further purification.

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