반응 #1010883

반응 방정식

carbazole

1-bromo-2-iodobenzene

potassium carbonate

→

9-(2-bromophenyl)-9H-carbazole

용매

xylene

반응 조건

후처리

1. 1
   추출extracted with ethyl acetate
2. 2
   건조dried with anhydrous magnesium sulfate
3. 3
   기타to remove moisture
4. 4
   기타the solvent was removed under reduced pressure
5. 5
   기타Silica gel column separation
6. 6
   기타thus obtaining a compound from which the solvent
7. 7
   기타was then removed under reduced pressure
8. 8
   기타drying

실험 절차

1.672 g of carbazole, 1.6 mL of 1-bromo-2-iodobenzene, 2.7646 g of potassium carbonate, 95 mg of copper iodide and 25 mL of xylene were refluxed in a nitrogen atmosphere. The mixture was cooled to room temperature, extracted with ethyl acetate, and dried with anhydrous magnesium sulfate to remove moisture, and the solvent was removed under reduced pressure. Silica gel column separation using a hexane solvent was conducted, thus obtaining a compound from which the solvent was then removed under reduced pressure, followed by vacuum drying, yielding 9-(2-bromophenyl)-9H-carbazole as a desired white solid intermediate.

출처