반응 #1005987

ord-1128576544784214b3281b40ef0f21cc

반응 방정식

NC=Cc1ccccc1
N-benzylidenemethylamine
O=Cc1ccc2ccccc2c1
2-naphthaldehyde
[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1
tosylmethylisocyanide
O=C([O-])[O-].[K+].[K+]
K2CO3
→
c1ccc2cc(-c3cnco3)ccc2c1
5-(2-naphthyl)-1,3-oxazole
Cn1cncc1-c1ccc2ccccc2c1
1-methyl-5-(2-naphthyl)-1H-imidazole

반응물

NC=Cc1ccccc1
N-benzylidenemethylamine
O=Cc1ccc2ccccc2c1
2-naphthaldehyde
[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1
tosylmethylisocyanide
O=C([O-])[O-].[K+].[K+]
K2CO3

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Reaction of N-benzylidenemethylamine 28i or 2-naphthaldehyde 29i and tosylmethylisocyanide (Tosmic) with K2CO3 as the base yielded 1-methyl-5-(2-naphthyl)-1H-imidazole 28 or 5-(2-naphthyl)-1,3-oxazole 29, respectively:

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09271963B2uspto-grants-2016_03