반응 #1005986

반응 방정식

phenol

4-bromo-2-cyclohex-2-enyl-phenol

MCPBA

→

8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol

용매

benzene

반응 조건

후처리

1. 1
   기타A solid is precipitated out
2. 2
   여과filtered
3. 3
   농축The filtrate is concentrated under vacuum
4. 4
   기타chromatographed (10% EtOAc in hexanes)

실험 절차

A solution of the phenol and MCPBA in benzene is refluxed overnight. A solid is precipitated out and filtered. The filtrate is concentrated under vacuum and chromatographed (10% EtOAc in hexanes) to give 8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol 108 as clear oil, 0.66 g, 39%.

출처