반응 #1005959

반응 방정식

(2-ethylsulfanylphenyl) (2-nitro-4-trifluoromethylbenzylidene)amine

triethyl phosphite

→

2-(2-ethylsulfanylphenyl)-6-trifluoromethyl-2H-indazole

수율 78.9%

반응 조건

후처리

1. 1
   농축concentrated under reduced pressure

실험 절차

A mixture of 777 mg of (2-ethylsulfanylphenyl) (2-nitro-4-trifluoromethylbenzylidene)amine and 3 ml of triethyl phosphite was stirred at 100° C. for 15 minutes and then concentrated under reduced pressure. The resulting residue was applied to a silica gel column chromatography to obtain 558 mg of 2-(2-ethylsulfanylphenyl)-6-trifluoromethyl-2H-indazole (hereinafter, referred to as Compound of Present Invention 1).

출처