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NCc1ccc(F)cc1F

CNC(=O)c1cc(N)c(F)cc1F
Reaction #6961
5-amino-2,4-difluoro-N-methylbenzamide
수율 41.0%DOI: 10.6084/m9.figshare.5104873.v1
NC(=O)c1c(F)c(F)c(F)c(C(N)=O)c1F
Reaction #46940
tetrafluoroisophthalamide
수율 98.9%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)C[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1C(C(=O)O)c1ccc(F)cc1F
Reaction #73895
(2RS)-2-(2,4-difluorophenyl)-2-[(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-isobutyl-2,5-dioxopiperazin-1-yl]-ethanoic acid
수율 69.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)C[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1[C@@H](C(=O)N(C)C)c1ccc(F)cc1F
Reaction #73896
(2R)-2-(2,4-difluorophenyl)-2-[(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-isobutyl-2,5-dioxopiperazin-1-yl]-N,N-dimethylethanamide
DOI: 10.6084/m9.figshare.5104873.v1
CS(=O)(=O)OCCNC(=O)c1ccc(F)cc1F
Reaction #79280
2-[(2,4-difluorobenzoyl)amino]ethyl methanesulfonate
수율 72.1%DOI: 10.6084/m9.figshare.5104873.v1
NC1=N[C@@]2(c3cc(-c4cncnc4)c(F)cc3F)CO[C@H](CF)[C@H]2CS1
Reaction #155562
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1OC[C@@](NC(=S)NC(=O)c2ccccc2)(c2ccc(F)cc2F)[C@@H]1CO
Reaction #155565
title compound
수율 82.8%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1OC[C@]2(c3ccc(F)cc3F)N=C(NC(=O)c3ccccc3)SC[C@H]12
Reaction #155566
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1OC[C@]2(c3cc(Br)c(F)cc3F)N=C(NC(=O)c3ccccc3)SC[C@H]12
Reaction #155567
desired compound
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1cc([C@]23CO[C@@H](CO)C[C@H]2CSC(N)=N3)c(F)cc1F
Reaction #155579
5-[(4aR,6R,8aS)-2-amino-6-(hydroxymethyl)-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-2,4-difluorobenzonitrile
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NC1=N[C@@]2(c3cc(Br)c(F)cc3F)CO[C@@H](CO)C[C@H]2CS1)c1ccccc1
Reaction #155580
product
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1cc([C@]23CO[C@@H](CF)C[C@H]2CSC(NC(=O)c2ccccc2)=N3)c(F)cc1F
Reaction #155581
N-[(4aR,6R,8aS)-8a-(5-cyano-2,4-difluorophenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-yl]benzamide
DOI: 10.6084/m9.figshare.5104873.v1
N#Cc1cc([C@]23CO[C@@H](CF)C[C@H]2CSC(N)=N3)c(F)cc1F
Reaction #155582
5-[(4aR,6R,8aS)-2-amino-6-(fluoromethyl)-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-2,4-difluorobenzonitrile
DOI: 10.6084/m9.figshare.5104873.v1
COC[C@H]1C[C@H]2CSC(N)=N[C@@]2(c2cc(C#N)c(F)cc2F)CO1
Reaction #155584
5-[(4aR,6R,8aS)-2-amino-6-(methoxymethyl)-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-2,4-difluorobenzonitrile
DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2cc(CNCC(F)(F)F)c(F)cc2F)CO1
Reaction #155592
product
수율 106.2%DOI: 10.6084/m9.figshare.5104873.v1
C[C@H]1C[C@H]2CSC(N)=N[C@@]2(c2cc(CNCC(F)(F)F)c(F)cc2F)CO1
Reaction #155593
product
DOI: 10.6084/m9.figshare.5104873.v1
CNC(=O)c1cc(N)c(F)cc1F
Reaction #168641
title compound
수율 77.6%DOI: 10.6084/m9.figshare.5104873.v1
NC(CS(=O)(=O)c1ccccc1)=NNC(=O)c1ccc(F)cc1F
Reaction #175225
DOI: 10.1039/C8SC04228D
COc1ccc(C(Nc2cc(C(N)=O)c(F)cc2F)C(=O)O)cc1OC
Reaction #181651
DOI: 10.1039/C8SC04228D
CCCCCCN(Cc1ccc(F)cc1F)C(=O)C(C)(C)CCC
Reaction #187522
DOI: 10.1039/C8SC04228D
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