2,4-diamino-6-chloropyrimidine-5-carbonitrile

C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1-c1ccccn1

Reaction #162502

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

Cc1n[nH]c(C)c1-c1cc2c(ccn2C)nc1[C@H](C)Nc1nc(N)nc(N)c1C#N

Reaction #162503

수율 55.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1-c1ccnc(O)c1

Reaction #162504

수율 46.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

CC(Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CCC(C)(O)CC1

Reaction #162508

수율 49.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1C1CCOCC1

Reaction #162511

수율 28.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

Cc1noc(C)c1-c1cc2c(ccn2C)nc1[C@H](C)Nc1nc(N)nc(N)c1C#N

Reaction #162514

수율 56.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

CC(Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CC(O)C1

Reaction #162521

수율 5.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

COC1CN(c2cc3c(ccn3C)nc2[C@H](C)Nc2nc(N)nc(N)c2C#N)C1

Reaction #162523

수율 15.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

CC(Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CC(F)(F)C1

Reaction #162524

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

CC(Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CC2(COC2)C1

Reaction #162525

title compounds

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

C[C@@H](Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CCOCC1

Reaction #162526

수율 45.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09

C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccnc1

Reaction #1594178

(S)-2,4-diamino-6-((1-(5-chloro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile

수율 166.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_12

C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2ccn(C)c2cc1N1CCN(C(=O)OC(C)(C)C)CC1

Reaction #2292796

수율 36.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_06