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C(C(F)(F)F)O

C[C@H](C(=O)N1C[C@@H](O)CCc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21)c1ccccc1
Reaction #46133
(S)-1-[(S)-3-Hydroxy-7-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]-2-phenyl-propan-1-one
DOI: 10.6084/m9.figshare.5104873.v1
O=C(NO)c1ccc(OCCNC(=O)c2oc3ccccc3c2COCC(F)(F)F)cc1
Reaction #57983
title compound
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(Nc2nc(COCC(F)(F)F)c(C)c(C(C)=O)n2)ccc1-n1cnc(C)c1
Reaction #87342
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C=C(OCC)c1cc(C(C)OCC(F)(F)F)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1
Reaction #87345
title product
DOI: 10.6084/m9.figshare.5104873.v1
COc1cc(Nc2nc(C(C)=O)cc(C(C)OCC(F)(F)F)n2)ccc1-n1cnc(C)c1
Reaction #87346
title compound
DOI: 10.6084/m9.figshare.5104873.v1
C=C(OCC)c1nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)nc(COCC(F)(F)F)c1C
Reaction #87389
title compound
수율 48.0%DOI: 10.6084/m9.figshare.5104873.v1
N[C@H]1CC[C@H](CCN2CCC(c3noc4ccc(F)cc34)CC2)CC1.O=C(O)C(F)(F)F
Reaction #160031
white solid
수율 100.0%DOI: 10.6084/m9.figshare.5104873.v1
CC=Cc1cc(C(OCc2ccccc2)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(C(=O)CN2C(=O)NC(C)(c3cnc4c(c3)OCCO4)C2=O)CC1
Reaction #182450
DOI: 10.1039/C8SC04228D
Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2ccccc2)c1
Reaction #185800
DOI: 10.1039/C8SC04228D
O=C(NC1CCCCC1O)c1nc(-c2ccc(Cl)c(Cl)c2)c(OCC(F)(F)F)nc1C(F)(F)F
Reaction #200583
DOI: 10.1039/C8SC04228D
CC(C)(C)c1cc(NC(=O)Nc2ccc(C(=O)N3CCN(Cc4ccc(C(O)(C(F)(F)F)C(F)(F)F)cc4)CC3)cc2F)no1
Reaction #209445
DOI: 10.1039/C8SC04228D
CC(C(=O)N1CC(O)CCc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21)c1ccccc1
Reaction #213431
DOI: 10.1039/C8SC04228D
C[C@@H](n1cnn(-c2ccc(OCC(F)(F)F)cc2)c1=O)[C@@]1(c2ccc(F)cc2F)CO1
Reaction #216334
4-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-2-[4-(2,2,2-trifluoroethoxy)phenyl]-3(2H,4H)-1,2,4-triazolone
수율 48.4%DOI: 10.6084/m9.figshare.5104873.v1
C[C@@H](n1nnn(-c2ccc(OCC(F)(F)F)cc2)c1=O)[C@@]1(c2ccc(F)cc2F)CO1
Reaction #216352
1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-4-[4-(2,2,2-trifluoroethoxy)phenyl]-5(1H,4H)-tetrazolone
수율 41.7%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cscc1-c1ccccc1C(Oc1cc(-c2ccc(CC(N)C(=O)O)cc2)nc(N)n1)C(F)(F)F
Reaction #225032
DOI: 10.1039/C8SC04228D
O=C(Nc1ccccc1)Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F
Reaction #226617
DOI: 10.1039/C8SC04228D
N#Cc1cc(-c2nc(-c3cccc4c(CCC(=O)O)nccc34)no2)ccc1OCC(F)(F)F
Reaction #244772
DOI: 10.1039/C8SC04228D
CC=Cc1cc(C(OCc2ccccc2)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(C(=O)CN2C(=O)NC(C)(c3ccc(OC(C)C)cn3)C2=O)CC1
Reaction #253463
DOI: 10.1039/C8SC04228D
COc1cncc(-c2ccc(C(Oc3cc(-c4ccc(CC(NC(=O)OC(C)(C)C)C(=O)O)cc4)nc(N)n3)C(F)(F)F)c(F)c2)c1
Reaction #253914
DOI: 10.1039/C8SC04228D
O=c1[nH]c2c(c(=O)n1CCCN1CCN(c3ccccc3OCC(F)(F)F)CC1)CCCC2
Reaction #265909
DOI: 10.1039/C8SC04228D
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